HR Business Partner & Operations in Amsterdam

Help bring breakthrough therapies to patients worldwide.

About VectorY: VectorY is a fast-growing biotech company developing long-lasting therapies for neurodegenerative diseases, based at Amsterdam Science Park. We combine gene therapy and antibody engineering to pursue new possibilities where medical need is high. With ~80 professionals across Amsterdam, Europe and the US, we are building momentum, and scaling our organisation and culture thoughtfully.

At VectorY, innovation and collaboration are not just values. They are how we will achieve our ambition. We believe the best ideas emerge when people challenge each other openly, work across boundaries, and stay focused on what is right for the organisation. We embrace diversity while striving to function as one cohesive, mission-driven team.

The role: This is a genuinely varied and impactful role. You will own day-to-day HR operations (typically no more than half a day per week) while actively business partnering ~60–65 on-site employees and leading key people projects. You will be the go-to HR contact for managers and employees, find smarter ways to run processes, and help build a stronger people foundation; as part of a team of four, reporting to the (interim) Chief People Officer. You will work closely with our dedicated recruiter (on-site one day a week) and your US counterpart based in Boston. In a typical week you might improve a process in HiBob, handle a few HR admin tasks, meet with people managers seeking advice, progress a strategic project, and connect with a vendor from our network - whilst staying open to whatever emerges in a fast-moving organisation.

This role is for you if you are equally comfortable in the detail and the bigger picture; handling payroll and contracts, driving process improvement, supporting managers on real people challenges, and contributing to strategic HR initiatives, sometimes all in the same week.

What you'll do:

• Own the end-to-end employee experience, from preboarding to offboarding, for employees in the Netherlands and a small number in France and the UK.
• Act as the primary HR business partner for people leaders and employees.
• Manage HR administration: contracts, leave, absence, and related processes, with a continuous eye for improvement.
• Lead process improvement initiatives: payroll, automation, vendor contracts, and system optimisation (we use HiBob).
• Drive and support strategic HR projects, co-created quarterly with the full HR team.
• Collaborate weekly with HR team colleagues on where and how to create impact.

What you bring:

• 5+ years of experience in HR Operations, People Operations or a generalist HR role.
• A strong sense of what good HR looks like, and the ambition to build it.
• The ability to prioritise effectively and switch between operational tasks, process improvement and strategic projects.
• Enthusiasm to work in a dynamic and international environment.
• Structure and detail orientation, with a pragmatic, hands-on mindset.
• Confident business partnering skills: you support managers and employees with honesty and care.
• Experience with HRIS systems; HiBob experience is a strong plus.
• Familiarity with Dutch payroll processes or working with a payroll provider is a plus.

Who you are: You are trustworthy and accurate, and people feel safe coming to you. You are proactive, you identify issues and improvements without waiting for permission. You think creatively about solutions and take a long-term view, while staying grounded in day-to-day reality. You are self-organised, flexible when priorities shift, and genuinely energised by making a real difference in a growing organisation. You build relationships easily, and you care about getting things right — both for the organisation and for the people in it.

What we offer:

• A close-knit HR team of four, working in an open and constructive way, with your manager based in Amsterdam, a US counterpart in Boston, and a dedicated recruiter on-site one day a week.
• 32–40 hours per week; 3 days in-office.
• Annual salary of €70,000–€85,000, based on experience.
• 12% discretionary annual bonus.
• 30 holidays on a full-time basis.
• The opportunity to shape HR at an exciting moment in VectorY's journey, with real scope to grow personally and professionally, lead initiatives, and make a visible impact.
• A dynamic, international environment at an ambitious biotech with a mission that matters.