Overview
Join Cradle as a Senior Scientist in the Large Libraries group to develop high-throughput protein library screening methods that feed our AI-driven platform. You’ll pioneer workflows for screening vast libraries (≥10^6 data points) and integrate results with ML models to accelerate protein optimization. Collaborate across biology and ML teams to shape the platform and impact biotech applications. This is an opportunity to push methodological boundaries at a startup with strong runway and global teams.
Arbeidsvoorwaarden / Benefits
- competitive salary
- equity stake
- wide range of benefits
- career progression opportunities
Verantwoordelijkheden
- Develop and optimize workflows for high-throughput protein library screening and characterization (>10^6 data points)
- Build and optimize in vitro and cell-based assay pipelines across multiple display and screening modalities
- Design, build, and execute experimental frameworks for library construction, screening, and data generation at scale
- Establish robust and repeatable assays with statistical rigor for ML model training, evaluation, and optimization
- Drive and lead projects from experimental design through data delivery
- Identify opportunities to improve throughput, data quality, repeatability, and workflow efficiency
- Collaborate with a cross-functional team to troubleshoot complex technical challenges and iterate on solutions
- Cross-functional Collaboration: Partner with the ML team to define data requirements and integrate experimental outputs into the ML pipeline
- Communicate results, insights, and technical challenges effectively across disciplines
- Contribute to shaping the scientific direction of the Large Libraries team and meaningfully contribute to the advancement of the Cradle platform
Belangrijkste vereisten
- PhD in biochemistry, molecular biology, biophysics, synthetic biology, bioengineering, or a related field
- Demonstrated creativity in method development: invention or substantial adaptation of workflows
- Excitement to learn, contribute, and drive innovation in an early-stage startup environment
- Strong verbal and written communication skills in English; proactive in sharing results and challenges
- Ability to run multiple projects simultaneously with well-documented processes and organized data
- Cross-functional collaboration
- English communication (verbal and written)
- Adaptability in a fast-paced startup
- High-throughput screening workflows
- Protein variant libraries (e.g., antibodies)
- Yeast display and FACS capabilities
Scientist, Large Libraries in Amsterdam werkgever: Jobrapido
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